Product Overview

Kisspeptin-10 (Kp-10) is a synthetic decapeptide corresponding to the C-terminal fragment of kisspeptin-54 (metastin), the endogenous ligand of the KISS1/GPR54 receptor. It plays a central role in hypothalamic-pituitary-gonadal (HPG) axis signaling and is widely used in preclinical research on reproductive endocrinology, GnRH pulsatility, and neuroendocrine regulation. This product is supplied as a high-purity lyophilized powder and is intended strictly for controlled laboratory research—not for human or veterinary use.

Key Features

Peptide Component: Kisspeptin-10 (Human)

Peptide Type: Decapeptide fragment of metastin (residues 45-54); endogenous agonist of the KISS1/GPR54 receptor

Amino Acid Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 (YNWNSFGLRF-NH2)

Molecular Formula: C63H83N17O14

Molecular Weight: ~1302.5 Da

CAS Number: 374675-21-5

Form: White to off-white lyophilized powder

Purity: ≥99% (COA verified)

Intended Research Applications

Investigation of GnRH pulse frequency and LH/FSH secretion within the HPG axis
Studies of reproductive endocrinology, puberty onset, and fertility signaling pathways
Exploration of KISS1/GPR54 receptor activation and downstream intracellular signaling
Preclinical models examining neuroendocrine, metabolic, and endocrine regulation
Research into hypogonadotropic hypogonadism, infertility, and related reproductive disorders

Product Attributes

Attribute	Details
CAS Number	374675-21-5
Sequence	YNWNSFGLRF-NH2
Molecular Formula	C63H83N17O14
Molecular Weight	~1302.5 Da
Purity	≥99% (COA verified)
Storage	-20 ± 5°C, protect from light and moisture
Appearance	White to off-white lyophilized powder
Research Areas	Reproductive Endocrinology, HPG Axis, GnRH/LH/FSH Regulation, Neuroendocrinology

Compliance Disclaimer

For Research Use Only: This product is not intended for human or veterinary use. Supply is strictly limited to laboratory research, analytical assay development, or investigative procedures only.Not for Human Consumption: Any clinical or diagnostic use, or use as a drug, food, or cosmetic is strictly prohibited.Handling Precautions: Employ appropriate personal protective equipment and follow institutional safety protocols for peptide handling and disposal.

Additional Information

Kisspeptin-10 should be reconstituted with 0.9% benzyl alcohol solution (Bacteriostatic Water) in accordance with your laboratory’s protocols.

No therapeutic or diagnostic claims are made for this compound. All statements relate exclusively to laboratory research findings.

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